Sunday, January 31, 2016

Pubmed / Google Scholar Studies on Electrolyzed Reduced Water and Cancer / Tumors


The ideas expressed on this website are from individual’s experiences ONLY and will not always apply to others. Any product mentioned on this website is not intended to diagnose, treat, cure, or prevent any disease, and the companies that make this type of water make NO CLAIMS to be able to prevent, treat, cure or reverse any type of disease.   






If you go to GOOGLE SCHOLAR, you will find that there are hundreds of studies showing the effects of electrolyzed reduced water (ERW) and Alkalilne Reduced Water (ARW) on cancer cells, tumors and other conditions.  If you are interested in learning how you can purchase one of these machines. just fill out the form on this blog. 



Here are just a few of the studies.


Electrolyzedreduced water scavenges active oxygen species and protects DNA from oxidative damage

S Shirahata, S Kabayama, M Nakano, T Miura… - Biochemical and …, 1997 - Elsevier
... can be produced in reduced water near the cathode during electrolysis of water... Strongly
electrolyzedreduced water, as well as ascorbic acid, (+)-catechin and tannic acid, completely ...
of ascorbic acid in a dose-dependent manner, suggesting that reduced water can scavenge ...

Reduced hemodialysis-induced oxidative stress in end-stage renal disease patients by electrolyzed reduced water

KC Huang, CC Yang, KT Lee, CT Chien - Kidney international, 2003 - nature.com
... Effects of hemodialysis (HD) and electrolyzed reduced water (ERW) supplement on PCOOH
(A), total antioxidant status (TAS) (B ... should be "active atomic hydrogen.""Active atomic hydrogen"
can be produced in reduced water near the cathode during electrolysis of water...

Inhibitory effect of electrolyzed reduced water on tumor angiogenesis

J Ye, Y Li, T Hamasaki, N Nakamichi… - Biological and …, 2008 - jlc.jst.go.jp
... A batch type electrolyzing device was used. ... Cell Culture and Reagents All electrolyzed alkaline
ERW was neutralized by adding 1ml of 10 minimum Eagle's ... pothesis of reduced water containing
metal nanoparticles and hydrogen molecule as follows: (1) Electrolysis produces ac ...

Hepatoprotective effect of electrolyzed reduced water against carbon tetrachloride-induced liver damage in mice

CF Tsai, YW Hsu, WK Chen, WH Chang… - Food and Chemical …, 2009 - Elsevier
... to microscopic examinations, severe hepatic fibrosis induced by CCl 4 was remarkably reduced
by the ... ERW, produced by electrolysis of water near the cathode, exhibits high pH, low dissolved
oxygen ... (2005) demonstrated that use of the electrolyzed hydrogen-saturated water ...

Telomere shortening in cancer cells by electrolyzed-reduced water

S Shirahata, E Murakami, K Kusumoto… - Animal cell technology: …, 2002 - Springer
Abstract Electroly-reduced water (ERW) which is produced near cathode during electrolysis 
of water scavenges reactive oxygen species and protects DNA from oxidative damage
(Shirahata et al., 1997). Most of cancer cells exhibit high telomerase activity to elongate ...

Electrolyzed and natural reduced water exhibit insulin-like activity on glucose uptake into muscle cells and adipocytes

M Oda, K Kusumoto, K Teruya, T Hara, T Maki… - Animal cell technology: …, 1999 - Springer
... Daily intake of electrolyzed alkaline reduced water produced near cathode by electrolysis is
believed to ... Preparation of reduced water Electrolyzed reduced water (ERW) was obtained from
ultrapure water containing 0.01% NaCl by using an electrolyzing device (type ...

Electrolyzed-reduced water reduced hemodialysis-induced erythrocyte impairment in end-stage renal disease patients

KC Huang, CC Yang, SP Hsu, KT Lee, HW Liu… - Kidney …, 2006 - nature.com
... compressed by the compression pump and supplied into a compartment for electrolysis through
... At the electric compartment, the supplied raw water was electrolyzed by direct current ... plate across
diaphragm and at the side of - electrode plate reduced water containing active ...

Roles of oxidation–reduction potential in electrolyzed oxidizing and chemically modified water for the inactivation of food-related pathogens

C Kim, YC Hung, RE Brackett - Journal of Food Protection®, 2000 - ingentaconnect.com
... HOCl is produced during electrolysis of saline-added water, and the amount of HOCl increases ...
Electrolyzed oxidizing water produced from ROX-20TA gener- ator (Hoshizaki Electric Inc ... the
addition of neutralizing buffer (Table 5). The neutralizing buffer also reduced the ORP ...

Reduced water for prevention of diseases

S Shirahata - Animal cell technology: basic & applied aspects, 2002 - Springer
... In an electrolyzing device, tap water is electrolyzed in anode room and cathode room separated
by ... Whereas, in the anode room, electrolyzed oxidized water (EOW) is produced ... In electrolysis,
H+ receives electron on the cathode to produce active hydrogen (H). Then H changes ...

[HTML] Advanced research on the health benefit of reduced water

S Shirahata, T Hamasaki, K Teruya - Trends in Food Science & Technology, 2012 - Elsevier
... Platinum-coated titanium electrodes are often used for electrolysis of water in the ...
Hydrogen-enriched electrolyzed water has been demonstrated to be safe in mutagenicity,
genotoxicity and ... fellows and graduate students who performed the research on reduced water ...

Protective mechanism of reduced water against alloxan-induced pancreatic β-cell damage: Scavenging effect against reactive oxygen species

Y Li, T Nishimura, K Teruya, T Maki, T Komatsu… - Cytotechnology, 2002 - Springer
... Electrolyzed-reduced water (ERW) was prepared by the electrolysis of ultra pure water
contain- ing 0.002 N NaOH using an electrolyzing device equipped with platinum-coated
titanium electrodes (Type TI-200s, Nihon Trim Co., Osaka, Japan). ...

Enhanced induction of mitochondrial damage and apoptosis in human leukemia HL-60 cells due to electrolyzed-reduced water and glutathione

CF Tsai, YW Hsu, WK Chen, YC Ho… - Bioscience, …, 2009 - Taylor & Francis
... The equipment for the electrolysis of water can control the pH regulator from pH ... DD water, double
distilled-deionized water ERW, electrolyzed-reduced water EOW, electrolyzed-oxidized water
... induced Bax up-regulation, and Bcl-2 down- regulation, and reduced pro-caspase ...

Electrolyzed Reduced Water Which Can Scavenge Active Oxygen Species Supresses Cell Growth and Regulates Gene Expression of Animal Cells

S Shirahata, S Kabayama, K Kusumoto… - New Developments and …, 1998 - Springer
... Electrolyzing voltage was changed to several to several tens V and currents several to 10 ... RP
+350 mV in water before electrolysis changes to -659 mV after electrolysis; 4.08 of ... 6 gene
expression in human osteosarcoma MG-63 cells by electrolyzed reduced water and reducing ...

Efficacy of electrolyzed oxidizing (EO) and chemically modified water on different types of foodborne pathogens

C Kim, YC Hung, RE Brackett - International Journal of Food Microbiology, 2000 - Elsevier
... To reduce the ORP readings of the EO waters and treatment solutions, iron (Iron Powder, Fisher ...
Electrolyzed oxidizing water produced from JAW-020 generator (Nippon Intek ... JAW EO water
and chlorine water (13 mg/l residual chlorine) generally reduced B. cereus population ...

[PDF] Platinum nanocolloid-supplemented hydrogen-dissolved water inhibits growth of human tongue carcinoma cells preferentially over normal cells

Y Saitoh, Y Yoshimura, K Nakano, N Miwa - Exp Oncol, 2009 - exp-oncology.com.ua
... It was assumed that a trace of Pt nanoclusters existed in electrolyzed reduced water by releasing ...
solutions, it is presumed that the HD-water pro- duced by electrolysis contains a ... Recently, it has
been showed that electrolyzed re- duced water supplemented with Pt nanoparticles ...

Electrolyzed reduced water supplemented with platinum nanoparticles suppresses promotion of two-stage cell transformation

R Nishikawa, K Teruya, Y Katakura, K Osada… - Cytotechnology, 2005 - Springer
... Key words: Active hydrogen, Antioxidant, Electrolyzed reduced water, 3-Methyl cholanthrene,
Phorbol- 12-myristate-13-acetate, Pt nanoparticles, Reactive oxygen species ... Elec- trolyzed
reduced water (ERW), which is produced near a cathode during electrolysis of water, is ...

Electrochemical removal of bromide and reduction of THM formation potential in drinking water

DE Kimbrough, IH Suffet - Water research, 2002 - Elsevier
... Bromine was historically manufactured by electrolyzing high bromide brines (0.2–6 g/L) in a ... is
that the stripping with CO 2 did remove the bromine from the electrolyzed water, although not ...
The future work needs to confirm the air-borne bromine in both electrolysis and carbon ...

Extension of the lifespan of Caenorhabditis elegans by the use of electrolyzed reduced water

H Yan, H Tian, T Kinjo, T Hamasaki… - Bioscience, …, 2010 - Taylor & Francis
... or alkaline ionized water, produced at the cathode site, and electrolyzed anode water ... ERW,
electrolyzed reduced water; CW, activated charcoal-treated water; DH, dissolved hydrogen ...
nanoparticles were assumed to be produced by the Pt-coated electrodes during electrolysis...

The melamine excretion effect of the electrolyzed reduced water in melamine-fed mice

YS Yoon, DH Kim, SK Kim, SB Song, Y Uh, D Jin… - Food and Chemical …, 2011 - Elsevier
... and the experimental group (MTF + ERW, n = 21) fed MTF and electrolyzed reduced water (ERW). ...
purified water (PW) and ERW were produced by the continuously electrolyzing apparatus (HDR ...
ERW was prepared by physical filtering followed by electrolysis and collected in a ...

Method and apparatus for producing electrolytic reduced water

S Shirahata, K Otsubo - US Patent 6,475,371, 2002 - Google Patents
... ie, electrolytic reduced water) applicable to cancer treatment, tap water has been electrolyzed
with NaCl ... When electrolyzing water, oxygen gas is generated at the anode side and hydrogen
gas at ... gas is generated because a hydrogen ion produced by the electrolysis and an ...

Neutral pH hydrogen-enriched electrolyzed water achieves tumor-preferential clonal growth inhibition over normal cells and tumor invasion inhibition concurrently with …

Y Saitoh, H Okayasu, L Xiao, Y Harata… - … and Clinical Cancer …, 2008 - ingentaconnect.com
... fects against superoxide anion radicals of reduced water produced by electrolysis. Biophys. ... renal
disease patients by electrolyzed reduced water. Kid- ney Int. ... lyzed-reduced water reduced
hemodialysis-induced eryth- rocyte impairment in end-stage renal disease patients. ...

Suppressive Effect of Electrolyzed-Reduced Water on the Growth of CancerCells and Microorganisms

MT Komatsu, S Kabayama, A Hayashida… - Animal cell technology: …, 2001 - Springer
Abstract We investigated the suppressive effect of electrolyzed reduced water (ERW) on the
growth of not only various human cancer cells but also microorganisms such as gram-
negative Escherichia coli. ERW suppressed the growth of cancer cells, especially in soft- ...

Anti-diabetic effect of alkaline-reduced water on OLETF rats

D Jin, SH Ryu, HW Kim, EJ Yang, SJ Lim… - Bioscience, …, 2006 - Taylor & Francis
... 1) Hanaoka, K., Antioxidant effects of reduced water produced by electrolysis of sodium ... Shirahata,
S., Kabayama, S., Nakano, M., Miura, T., Kusumoto, K., Gotoh, M., Hayashi, H., Otsubo, K.,
Morisawa, S., and Katakura, Y., Electrolyzed-reduced water scavenges active ...

Protective effect of electrolyzed reduced water on the paraquat-induced oxidative damage of human lymphocyte DNA

EJ Park, KK Ryoo, YB Lee, JK Lee… - Journal of the Korean …, 2005 - koreascience.or.kr
... Abstract. Electrolyzed reduced water (ERW), showing extremely negative oxidation-reduction
potential, was ... N., Takumi, M., Kenichi, K., Miho, G., Hidemitsu, H., Kazumichi, O., Shinkatsu, M.
and Yoshinori, K. (1997) Electrolyzed-reduced water scavenges active ... Clin. Cancer Res. ...

Mechanism of the lifespan extension of Caenorhabditis elegans by electrolyzed reduced water—participation of PT nanoparticles

H Yan, T Kinjo, H Tian, T Hamasaki… - Bioscience, …, 2011 - Taylor & Francis
... by a filtration system (Millipore, Billerica, MA) was supplemented with 2mM NaOH and electrolyzed
for 1h ... On the other hand, it has been observed that during the electrolysis process a trace amount
of ... Hence, in this study we reduced the treatment with paraquat from 0.4 to 0.2 M ...

The immunological effects of electrolyzed reduced water on the Echinostoma hortense infection in C57BL/6 mice

KJ Lee, D Jin, BS Chang, YC Teng… - Biological and …, 2009 - jlc.jst.go.jp
... filtered water (FW) and ERW were produced by the continuously electrolyzing apparatus (BTM ...
ERW was prepared by physical filtering fol- lowed by electrolysis and collected ... In support of this
hypothesis, Vorobjeva29) has reported that electrolyzed reduced water maintains an ...

The use of the comet assay in the study of human nutrition and cancer

GR Wasson, VJ McKelvey-Martin, CS Downes - Mutagenesis, 2008 - Oxford Univ Press
... cells [lycopene decreased oxidative lesions (14)], melanocytes (lycopene caused a reduction
in UVA ... human breast cells using the comet assay and found that it reduced DNA damage.
Genistein was shown to reduce hydrogen peroxide-induced damage in human prostate cells ...

Electrolyzed reduced water induces differentiation in K-562 human leukemia cells

T Komatsu, Y Katakura, K Teruya, K Otsubo… - Animal cell technology: …, 2003 - Springer
... ERW produced near the cathode during electrolysis of water contains high dissolved molecular
hydrogen, exhibits a ... of ERW Ultrapure water containing 0.OO2N NaOH was electrolyzed by an
electrolyzing device equipped ... Electrolyzed water in the cathode was used as ERW. ...

Selective stimulation of the growth of anaerobic microflora in the human intestinal tract by electrolyzed reducing water

NV Vorobjeva - Medical hypotheses, 2005 - Elsevier
... in favour of the hypothesis that the primary target for electrolyzed reducing water is the ... according
to the theory put forward by the Japanese researches, electrolysis of large ... The idea that
antioxidants including reduced water act positively on eukaryotic cells of macroorganism is ...

[PDF] Water, the chemistry of life

H Hayashi - Part IV. Explore, 1995 - pds18.egloos.com
... When tap water is electrolyzed into ionized water, its reduced water has a pH of about 9 and
the oxidized water a pH of about 4. Even if you make alkaline ... In 1965 the Ministry of Welfare of
Japan announced that reduced water obtained from electrolysis can prevent ...

The balneotherapy effect of hydrogen reduced water on UVB-mediated skin injury in hairless mice

RM Ignacio, YS Yoon, MEJ Sajo, CS Kim… - Molecular & Cellular …, 2013 - Springer
... 1. Alkaline reduced water (ARW) was produced by the continuously electrolyzing apparatus
(HDr Co ... effects against superoxide anion radicals of reduced water produced by electrolysis...
induced oxidative stress in end-stage renal disease patients by electrolyzed reduced water...

Electrochemical reduction of pyrimidine, cytosine and related compounds: polarography and macroscale electrolysis

DL Smith, PJ Elving - Journal of the American Chemical Society, 1962 - ACS Publications
... gave considerably higher currents and were more difi- cult to reduce by at least ... selected deriv-
atives, which included not only polarography but also electrolysis and coulometry ... with chemical
and spectrophotometric examina- tion of the electrolytically reduced solutions, shows ...

Nitrate removal by a paired electrolysis on copper and Ti/IrO 2 coupled electrodes–influence of the anode/cathode surface area ratio

D Reyter, D BélangerL Roué - Water research, 2010 - Elsevier
... Recently, an electrochemical process in which nitrate ions are reduced to ammonia at the cathode,
whereby the ... After each electrolysis, NH 3 , N 2 H 4 and NH 2 OH concentrations in solution ... of
OH ads increase the rate of the electron-transfer steps and reduce the overpotential ...

Hydrogen-rich electrolyzed warm water represses wrinkle formation against UVA ray together with type-I collagen production and oxidative-stress diminishment in …

S Kato, Y Saitoh, K Iwai, N Miwa - Journal of Photochemistry and …, 2012 - Elsevier
... TOA Corp., Tokyo, Japan) and achieved to 41 °C. A batch type electrolyzing device was ... Application
of hydrogen-rich electrolyzed warm water (HW) and Immunostaining for type- I collagen in ... This
device can supply HW by electrolysis of tap-water and hold dissolved hydrogen at ...

Implantable MEMS drug delivery device for cancer radiation reduction

H GenslerR SheybaniPY Li, R Lo… - … (MEMS), 2010 IEEE …, 2010 - ieeexplore.ieee.org
... often involves radiation therapy which results in severe systemic side effects; reduction of the
dose ... actuator format [3] was adopted to separate the drug from the electrolyzed fluid and ... The

electrolysis actuator consists of a pair of interdigitated electrodes, electrolyte (in this case ...

Method for producing electrolytic water and apparatus for producing the same

T Nakamura - US Patent 5,858,202, 1999 - Google Patents
... Water electrolyzing apparatus. ... US8319654, Jun 19, 2009, Nov 27, 2012, Tennant Company,
Apparatus having electrolysis cell and indicator light illuminating ... US9005410 *, Aug 21, 2012,
Apr 14, 2015, Yun-Chi Hung, Continuous electrolyzed oxidizing/reduction water generator ...

Electrolytic ionized water producing apparatus

K Yamanaka, T Imaoka, T Futatsuki… - US Patent …, 1997 - Google Patents
... Electrolyzing conditions: ... Electrolysis unit having a three-compartment cell comprising cathode
chamber, anode chamber, and a saline solution ... Aug 12, 2010, Yusho Arai, Electrolyzed water
manufacturing device, electrolyzed water manufacturing method, and electrolyzed water...

Electrolysed-reduced water dialysate improves T-cell damage in end-stage renal disease patients with chronic haemodialysis

KC Huang, SP Hsu, CC Yang, P Ou-Yang… - Nephrology Dialysis …, 2010 - ERA-EDTA
... scavenger could be active atomic hydrogen, which can be produced in ERW during water

electrolysis... of IL-2, IL-4 and IL-10 was significantly reduced in HD ... Electrolyzed-reduced water
reduced hemodialysis-induced erythrocyte impairment in end-stage renal disease patients. ...

[PDF] Molecular hydrogen as an emerging therapeutic medical gas for neurodegenerative and other diseases

K Ohno, M Ito, M Ichihara, M Ito - Oxidative medicine and …, 2012 - downloads.hindawi.com
... as efficiently as hydroxyl radical in vitro [6], hydrogen can efficiently reduce nitric-oxide-(NO ... A
part of hydrogen effects may thus be attributed to the reduced production of ... s). In addition, using
murine RAW264 macrophage cells, we demonstrated that hydrogen reduces LPS/IFNγ ...

Inactivation of E. coli O157: H7 on blueberries by electrolyzed water, ultraviolet light, and ozone

C Kim, YC Hung - Journal of food science, 2012 - Wiley Online Library
... Ozone treatment with 4000 mg/L reduced E. coli O157:H7 by only 0.66 and 0.72 log ... acid (from
10 to 100 mg/L). Bactericidal effects are due to an electrolyzed acidic aqueous ... Several studies
were reported as using UV to inhibit or reduce the growth of pathogenic and spoilage ...

Hydrogen resuscitation, a new cytoprotective approach

XF Zheng, XJ Sun, ZF Xia - Clinical and Experimental …, 2011 - Wiley Online Library
... downstream signal transduction, which subsequently inhibited NADPH oxidase activity and
reduced the hydrogen ... Many anti-oxidants have been shown to reduce ROS levels in
oxidation-related ... Second, hydrogen selectively reduces ·OH, the most reactive ROS, and does ...

Light work with water

NS Lewis - Nature, 2001 - nature.com
... Back in 1972 a seminal paper 4 described the sunlight-assisted electrolysis of water, using ... the
solar spectrum, and that the photoexcited electrons still retain enough energy to reduce water
to H 2 ... in moles) of H 2 and O 2 produced exceeds the amount of reducing equivalents in ...

[HTML] Hydrogen in drinking water reduces dopaminergic neuronal loss in the 1-methyl-4-phenyl-1, 2, 3, 6-tetrahydropyridine mouse model of Parkinson's disease

K Fujita, T Seike, N Yutsudo, M Ohno, H Yamada… - PloS one, 2009 - journals.plos.org
... of superoxide (O 2 • − ) detected by intravascular injection of dihydroethidium (DHE) was not
reduced significantly ... The H 2 content in H 2 water, made by either dissolving electrolyzed hydrogen
into pure ... water was made by directly bubbling H 2 gas produced by electrolysis (H 2 ...

Studies on the Properties and Real Existence of Aqueous Solution Systems that are Assumed to Have Antioxidant Activities by the Action of" Active Hydrogen"

A Hiraoka, M Takemoto, T Suzuki, A Shinohara… - Journal of health …, 2004 - jlc.jst.go.jp
... a) Electrolyzed reduced water, b) “I'm Fine,” c) Mineral-stick water, d) Hira tenryosui water ... The
antioxidant activities of these aque- ous solutions thus prepared without electrolysis or extraction ...
of the four aqueous solution systems and aqueous CFA were reduced depending on ...

Electrochemical reduction of purine, adenine and related compounds: polarography and macroscale electrolysis

DL Smith, PJ Elving - Journal of the American Chemical Society, 1962 - ACS Publications
... by examination of the precipitates obtained with sodium tetraphenyl- borate with a reduced
adenine solution ... solution (stirred over mercury in the coulometer cell, but not electrolyzed), does
not ... of TPB precipitate obtained in a series of four electrolyses from electrolysis of 0.250 ...

Neutral and acidic electrolyzed water as emergent sanitizers for fresh-cut mizuna baby leaves

A Tomás-Callejas, GB Martínez-Hernández… - Postharvest Biology and …, 2011 - Elsevier
... antimicrobial activity if EW is not supplied with H + , HOCl, and Cl 2 by electrolysis (Kiura et ... water,
as well as with NEW and AEW, total mesophilic counts were slightly reduced (<1 CFU ... range to
those reached by washing fresh-cut lettuce for 1 min in electrolyzed oxidizing water ...

[HTML] The 2011 medical molecular hydrogen symposium: an inaugural symposium of the journal medical Gas research

S Ohta, A Nakao, K Ohno - Medical gas …, 2011 - medicalgasresearch.biomedcentral. …
... mitochondrial disorders and inflammatory myopathies, and demonstrated a remarkable reduction
of several ... direct dental application of hydrogen water on injured regions reduced inflammation
and ... and induces production of peroxynitrite, and H 2 reduces peroxynitrite derived ...

Effectiveness of acidic oxidative potential water in preventing bacterial infection in islet transplantation.

M Miyamoto, K Inoue, Y Gu, M Hoki, S Haji… - Cell …, 1998 - europepmc.org
... Acidic oxidative potential water (also termed electrolyzed strong acid solution, function water,
or acqua oxidation ... in Japan, is a strong acid formed on the anode in the electrolysis of water ... It
has these physical properties: pH, from 2.3 to 2.7; oxidative-reduction potential, from ...

Direct electrochemical reduction of titanium dioxide to titanium in molten calcium chloride

GZ Chen, DJ Fray, TW Farthing - Nature, 2000 - nature.com
... These experiments indicated that it might be possible to electrochemically reduce TiO 2 directly
to the ... placing it in a titanium crucible filled with molten CaCl 2 and performing electrolysis (3.2
... It is surprising that TiO 2 , which is effectively an insulator, can be reduced so quickly. ...

Nitrate reduction using an electrode as direct electron donor in a biofilm-electrode reactor

HI Park, D kun Kim, YJ Choi, D Pak - Process Biochemistry, 2005 - Elsevier
... In order to reduce nitrates, physicochemical and biological processes have been proposed in
literature. ... for hydrogen production is 100% and the hydrogen produced by electrolysis of water ...
Nitrate can be biologically reduced using electrons from the cathode in the absence of ...



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